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<p begin="0:00:07.13" end="0:00:11.76">My own lab is interested in parasite control – mechanisms that control parasitic</p>
<p begin="0:00:11.77" end="0:00:14.84">diseases in sheep and cattle. The main focus of our work is a parasite called liver</p>
<p begin="0:00:14.85" end="0:00:20.49">fluke .It's a flat worm parasite that infects animals and humans – a significant</p>
<p begin="0:00:20.50" end="0:00:23.61">problem in Australia and an enormous problem around the world. </p>
<p begin="0:00:23.62" end="0:00:28.47">AgriBio has been designed to be inherently flexible into the future. It's</p>
<p begin="0:00:28.48" end="0:00:32.76">designed under a public-private partnership model, and the intent through all of</p>
<p begin="0:00:32.77" end="0:00:35.99">the design process has been to design a facility which is going to be capable of</p>
<p begin="0:00:36.00" end="0:00:40.64">delivering high-end science solutions for the next 25 years. So there's quite a</p>
<p begin="0:00:40.65" end="0:00:44.44">lot of crystal ball gazing in there, but we believe it's going to offer a facility</p>
<p begin="0:00:44.45" end="0:00:49.41">with world-class capabilities for growing plants and animals under various</p>
<p begin="0:00:49.42" end="0:00:53.41">levels of containment, and to really facilitate the collaboration between La</p>
<p begin="0:00:53.42" end="0:00:55.64">Trobe scientists and DPI staff. </p>
<p begin="0:00:55.65" end="0:00:58.61">The research that I'll perform at AgriBio will be mainly to continue with our</p>
<p begin="0:00:58.62" end="0:01:02.76">subsoil manuring work. This is a new technology we've developed. It involves</p>
<p begin="0:01:02.77" end="0:01:07.72">incorporating large amounts of organic matter into the subsoil. It transforms</p>
<p begin="0:01:07.73" end="0:01:11.49">the subsoil. There's a lot still we need to understand about the basic function of</p>
<p begin="0:01:11.50" end="0:01:13.84">the technology. </p>
<p begin="0:01:13.85" end="0:01:18.01">I work on plant diseases, looking at identification of plant diseases for plant</p>
<p begin="0:01:18.02" end="0:01:21.92">pathogens that are biosecurity pathogens, but also for long-term control of</p>
<p begin="0:01:21.93" end="0:01:24.44">pathogens on plants. </p>
<p begin="0:01:24.45" end="0:01:28.84">My research mainly covers four areas. The first one is looking at plant-soil</p>
<p begin="0:01:28.85" end="0:01:34.36">interactions, with a focus on rhizosphere chemistry and biochemistry. The</p>
<p begin="0:01:34.37" end="0:01:41.52">second area is impacts of climate change on soil processes. So these two projects</p>
<p begin="0:01:41.53" end="0:01:49.01">cover the effect of warming and the effect of elevated CO2 on the soil in the carbon</p>
<p begin="0:01:49.02" end="0:01:54.36">and nitrogen cycle. And the third area is in soil management, with a focus on the</p>
<p begin="0:01:54.37" end="0:02:00.59">management of soil acidity. And the final area is phytoremediation.  </p>
<p begin="0:02:00.60" end="0:02:07.39">In terms of impacts from this research, it's all about transforming the soil. It</p>
<p begin="0:02:07.40" end="0:02:12.39">enables us to increase rainfall use efficiency. It enables us to store, capture</p>
<p begin="0:02:12.40" end="0:02:17.24">and use extra rainfall in our crops, and to use it late in reproductive</p>
<p begin="0:02:17.25" end="0:02:21.44">development, which means it's used very efficiently. This delivers huge</p>
<p begin="0:02:21.45" end="0:02:24.36">productivity gains, and improvements in water use. </p>
<p begin="0:02:24.37" end="0:02:28.01">Probably the two major impacts I would envisage would be that one or two of the</p>
<p begin="0:02:28.02" end="0:02:32.44">molecules that we identify from our protein work could be worked up to be a</p>
<p begin="0:02:32.45" end="0:02:36.13">value-added vaccine. We would make a recombinant protein and evaluate that</p>
<p begin="0:02:36.14" end="0:02:40.19">protein in large animals, and if the initial trials were successful, we could then</p>
<p begin="0:02:40.20" end="0:02:43.29">talk to pharmaceutical companies to further develop those molecules as</p>
<p begin="0:02:43.30" end="0:02:46.29">commercial vaccines. </p>
<p begin="0:02:46.30" end="0:02:50.93">What we're working on is looking for long-term control options with plant</p>
<p begin="0:02:50.94" end="0:02:54.64">diseases. One of the pathogens I work on attacks apples, and we're working with</p>
<p begin="0:02:54.65" end="0:02:58.24">plant breeders to try and get apples that don't need spraying for example, in the</p>
<p begin="0:02:58.25" end="0:03:02.64">future. AgriBio will provide us with superb new facilities that are quarantine</p>
<p begin="0:03:02.65" end="0:03:06.89">containment and physical containment that allows us to do ou molecular work on</p>
<p begin="0:03:06.90" end="0:03:11.27">plant pathogens as well as marvellous glasshouses and new growth containment</p>
<p begin="0:03:11.28" end="0:03:12.44">facilities. </p>
<p begin="0:03:12.45" end="0:03:18.92">The main facilities which can help my research is the suite of world-class</p>
<p begin="0:03:18.93" end="0:03:23.04">glasshouses. </p>
<p begin="0:03:23.05" end="0:03:27.69">In terms of new research opportunities, AgriBio for me is going to open up a whole</p>
<p begin="0:03:27.70" end="0:03:32.61">new world of molecular biology. I'm basically an agronomist, working with crops</p>
<p begin="0:03:32.62" end="0:03:38.36">and soils, but we need to use the new tools in molecular biology to understand the</p>
<p begin="0:03:38.37" end="0:03:43.32">genes, the DNA, to help us understand what's going on. This opportunity will be</p>
<p begin="0:03:43.33" end="0:03:48.49">available with DPI in AgriBio because they have the people, they have the tools. </p>
<p begin="0:03:48.50" end="0:03:52.29">The benefits of AgrBio is that it's a collaboration between La Trobe University</p>
<p begin="0:03:52.30" end="0:03:56.64">scientists, and scientists from the Department of Primary Industries Victoria.</p>
<p begin="0:03:56.65" end="0:04:00.49">It will bring together over 400 scientists, staff and students from both</p>
<p begin="0:04:00.50" end="0:04:04.96">organisations in a collaborative institute that we hope will drive the future of</p>
<p begin="0:04:04.97" end="0:04:09.24">Victorian agriculture and biological sciences. </p>
<p begin="0:04:09.25" end="0:04:13.41">International collaborations mainly involve working with pharma groups,</p>
<p begin="0:04:13.42" end="0:04:17.47">pharma research driven groups across Australia, southern Australia and the</p>
<p begin="0:04:17.48" end="0:04:22.61">cropping areas from Western Australia to NSW working on this new technology –</p>
<p begin="0:04:22.62" end="0:04:27.21">subsoil manuring. We've recently made contact with a group of Punjab in India,</p>
<p begin="0:04:27.22" end="0:04:32.92">again trying to introduce our technology into their farming systems where they</p>
<p begin="0:04:32.93" end="0:04:35.41">have these problem subsoils. </p>
<p begin="0:04:35.42" end="0:04:38.93">One of the major collaborations I have is looking at the genomes of a couple of plant</p>
<p begin="0:04:38.93" end="0:04:43.99">pathogens – things that infect apples and pears, and looking at the sequence of</p>
<p begin="0:04:44.00" end="0:04:47.72">these fungi – their whole genome sequence. I'm working with New Zeland scientists</p>
<p begin="0:04:47.73" end="0:04:53.29">at the plant and food research organisation as well as scientists from Inra in</p>
<p begin="0:04:53.30" end="0:04:58.39">France, and a new collaboration with Korean scientists looks at a fungus that</p>
<p begin="0:04:58.40" end="0:05:02.59">infects nashi pear which we currently don't have in Australia. </p>
<p begin="0:05:02.60" end="0:05:07.21">When we relocate to AgriBio with colleague from DPI I anticipate that we'll be</p>
<p begin="0:05:07.22" end="0:05:11.44">working closely with the soils group. They have mastered the techniques of</p>
<p begin="0:05:11.45" end="0:05:16.29">identifying soil microbes using their molecular tools. We need to master those</p>
<p begin="0:05:16.30" end="0:05:21.19">techniques for our technology and I'm looking forward very much to actually</p>
<p begin="0:05:21.20" end="0:05:35.87">working with that group. </p>
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